2. Signaling Pathways
  3. Anti-infection
  4. Influenza Virus

Influenza Virus

Influenza Virus

Related Products

PDF 1.08 MB

Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0440R
    Germacrone (Standard)
    		Inhibitor
    Germacrone (Standard) is an analytical standard of Gemmacrone (HY-N0440). This product is intended for research and analytical applications. Germacrone (Standard) is a sesquiterpene compound with multiple biological activities. Germacrone (Standard) inhibits the H1N1 and H3N2 influenza A viruses and the influenza B virus. Germacrone (Standard) blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone (Standard) can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone (Standard) inhibits 5α-reductase and has anti-androgenic effect. Germacrone (Standard) has neuroprotective functions and can be used for the study of traumatic brain injury (TBI). Germacrone (Standard) also has antioxidant activity.
    Germacrone (Standard)
  • HY-D0214R
    Acid Red 94 sodium (Standard)
    		Inhibitor
    Acid Red 94 sodium (Standard) is the analytical standard of Acid Red 94 sodium. This product is intended for research and analytical applications. Acid Red 94 sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Acid Red 94 sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Acid Red 94 sodium exhibits antiviral activities.
    Acid Red 94 sodium (Standard)
  • HY-20685S
    Palmitoylethanolamide-d4
    		Inhibitor 99.9%
    Palmitoylethanolamide-d4 is the deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.
    Palmitoylethanolamide-d<sub>4</sub>
  • HY-135853S
    Molnupiravir-d7
    		Inhibitor 99.86%
    Molnupiravir-d7 is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza.
    Molnupiravir-d<sub>7</sub>
  • HY-164927
    AV5124
    		Inhibitor 99.11%
    AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor.
    AV5124
  • HY-N6807S
    Elemicin-d3
    		Inhibitor 98.53%
    Elemicin-d3 is deuterated labeled Pemafibrate (HY-17618). Pemafibrate is a highly selective PPARα agonist, with an EC50 of 1 nM.
    Elemicin-d<sub>3</sub>
  • HY-P1749
    Influenza HA (307-319)
    		98.55%
    Influenza HA (307-319) is 13 amino acids 307 to 319 fragment of Influenza HA. Influenza HA is a glycoprotein found on the surface of influenza viruses.
    Influenza HA (307-319)
  • HY-N5056
    DL-Goitrin
    		99.79%
    DL-Goitrin, also called (R, S)- report by the spring, consists of the epigoitrin (reported by the R- Spring) and the spring (-S- reported by spring), and the two mutually isomers, and the mixture is the ingredient of cruciferous vegetables.
    DL-Goitrin
  • HY-N2216
    Polygalasaponin XXXI
    Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection.
    Polygalasaponin XXXI
  • HY-135646
    Eleutheroside B1
    		Inhibitor 99.00%
    Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.
    Eleutheroside B1
  • HY-N0452R
    Hyperoside (Standard)
    		Inhibitor
    Hyperoside (Standard) is the analytical standard of Hyperoside. This product is intended for research and analytical applications. Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis.
    Hyperoside (Standard)
  • HY-P1783A
    M2e, human TFA
    		99.86%
    M2e, human TFA, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A. M2e, human TFA is a valid and versatile vaccine candidate to protect against any strain of human influenza A.
    M2e, human TFA
  • HY-N0453R
    Hypericin (Standard)
    		Inhibitor
    Hypericin (Standard) is the analytical standard of Hypericin. This product is intended for research and analytical applications. Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis.
    Hypericin (Standard)
  • HY-40354AS
    Tofacitinib-d3 citrate
    		Inhibitor 99.59%
    Tofacitinib-d3 (citrate) is deuterium labeled Tofacitinib (citrate). Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities.
    Tofacitinib-d<sub>3</sub> citrate
  • HY-165613
    Pam2Cys
    		Inhibitor 99.82%
    Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection.
    Pam2Cys
  • HY-B0510B
    Trimethoprim hydrochloride
    		Inhibitor 99.16%
    Trimethoprim hydrochloride is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim hydrochloride is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim hydrochloride has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim hydrochloride can inhibit infection of Influenza A virus in chick embryo when combinated with zinc.
    Trimethoprim hydrochloride
  • HY-N3035
    Tetrahydroepiberberine
    		Inhibitor 99.38%
    Tetrahydroepiberberine is a isoquinoline alkaloid isolated from Corydalis impatiens (Pall). Tetrahydroepiberberine has antifungal and selective inhibition against the PI-3 virus activities.
    Tetrahydroepiberberine
  • HY-N0053R
    Psoralen (Standard)
    		Inhibitor
    Psoralen (Standard) is the analytical standard of Psoralen. This product is intended for research and analytical applications. Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al.
    Psoralen (Standard)
  • HY-P991059
    VIS-410
    		Inhibitor 99%
    VIS-410 is an antibody inhibitor targeting the stem region of hemagglutinin (HA). VIS-410 inhibits influenza virus replication by blocking HA-mediated membrane fusion. VIS-410 exhibits broad-spectrum neutralization against influenza A viruses with group 1 and group 2 hemagglutinins, including subtypes such as H1N1, H3N2, H5N1, and H7N9 (H5N1 IC50 = 1.5 μg/mL). VIS-410 is applicable to research related to influenza A virus infection.
    VIS-410
  • HY-W269306
    Bonaphthone
    		Inhibitor
    Bonaphthone is an antiviral agent with anti-DNA and -RNA viral activities.
    Bonaphthone
Cat. No. Product Name / Synonyms Species Source
Cat. No. Product Name / Synonyms Application Reactivity